Now Open · Cambridge, OH

Sip, Stay,
Savor Every
Moment

Your neighborhood spot on Route 22 for freshly brewed coffee, hearty breakfast, and good times — from morning to midnight.

Explore Our Menu Find Us
Local Favorite
Open 7 Days
Coffee & Cocktails
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Fresh Coffee Daily

From bold espressos to smooth lattes, every cup is crafted with care using quality beans and fresh ingredients.

Hearty Kitchen

Breakfast all day, satisfying lunch plates, and fresh-made sandwiches. Real food made from scratch, every day.

Cocktails at Night

When the sun goes down, the bar comes alive. Craft cocktails, cold beers, and a lively atmosphere await.

Our Story

More Than a Cafe —
It's a Community

Route 22 Cafe has been a welcoming stop along Cadiz Road for years — a place where neighbors bump into friends, where the coffee is always hot, and where every guest is treated like family.

Whether you're grabbing a quick morning coffee before work, settling in for a leisurely lunch, or meeting friends for evening cocktails, we've got a seat with your name on it.

7
Days a Week
☕
Fresh Brewed
🍸
Full Bar
Interior of Route 22 Cafe with warm lighting and cozy seating
What People Say

Loved by Locals

"My go-to spot every morning. The coffee is consistently great and the staff makes you feel right at home. Best breakfast in Cambridge, hands down."

— A Happy Regular

"Love that this place transforms from a cozy coffee shop by day into a fun cocktail bar by night. Great atmosphere, solid drinks, and the food is delicious."

— A Local Foodie

"The avocado toast is to die for, and the iced coffee keeps me coming back. It's the kind of place where you actually want to linger and enjoy your day."

— A Weekend Visitor

Come See Us

Visit Route 22 Cafe

We're right on Route 22 in Cambridge — easy to find, impossible to forget.

Address

11103 Cadiz Rd
Cambridge, OH 43725-9634

Hours

Monday – Friday7:00 AM – 10:00 PM
Saturday8:00 AM – 11:00 PM
Sunday8:00 AM – 9:00 PM

Your Table's Waiting

Stop by 11103 Cadiz Rd, give us a call at (740) 260-3271, or just show up — we'll have a seat ready for you.

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